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Response to comment on “Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2”
Justin et al. suggested that in the crystal structure of a polycomb repressive complex 2 from Chaetomium thermophilum (ctPRC2) a flexible linker region but not the H3K27M cancer mutant peptide better fits the electron density. Based on our new data we agree with this alternative interpretation and p...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Science |
|---|---|
| Prif Awduron: | , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2016
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5724769/ https://ncbi.nlm.nih.gov/pubmed/28008038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaj2335 |
| Tagiau: |
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