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Response to comment on “Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2”

Justin et al. suggested that in the crystal structure of a polycomb repressive complex 2 from Chaetomium thermophilum (ctPRC2) a flexible linker region but not the H3K27M cancer mutant peptide better fits the electron density. Based on our new data we agree with this alternative interpretation and p...

詳細記述

保存先:
書誌詳細
出版年:Science
主要な著者: Jiao, Lianying, Liu, Xin
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5724769/
https://ncbi.nlm.nih.gov/pubmed/28008038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaj2335
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