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Response to comment on “Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2”
Justin et al. suggested that in the crystal structure of a polycomb repressive complex 2 from Chaetomium thermophilum (ctPRC2) a flexible linker region but not the H3K27M cancer mutant peptide better fits the electron density. Based on our new data we agree with this alternative interpretation and p...
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| Izdano u: | Science |
|---|---|
| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5724769/ https://ncbi.nlm.nih.gov/pubmed/28008038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaj2335 |
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