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Cholesterol-binding site of the influenza M2 protein in lipid bilayers from solid-state NMR

The influenza M2 protein not only forms a proton channel but also mediates membrane scission in a cholesterol-dependent manner to cause virus budding and release. The atomic interaction of cholesterol with M2, as with most eukaryotic membrane proteins, has long been elusive. We have now determined t...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Elkins, Matthew R., Williams, Jonathan K., Gelenter, Martin D., Dai, Peng, Kwon, Byungsu, Sergeyev, Ivan V., Pentelute, Bradley L., Hong, Mei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5724280/
https://ncbi.nlm.nih.gov/pubmed/29158386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715127114
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