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Cholesterol-binding site of the influenza M2 protein in lipid bilayers from solid-state NMR
The influenza M2 protein not only forms a proton channel but also mediates membrane scission in a cholesterol-dependent manner to cause virus budding and release. The atomic interaction of cholesterol with M2, as with most eukaryotic membrane proteins, has long been elusive. We have now determined t...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5724280/ https://ncbi.nlm.nih.gov/pubmed/29158386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715127114 |
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