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Cholesterol Interaction with the Trimeric HIV Fusion Protein gp41 in Lipid Bilayers Investigated by Solid-State NMR Spectroscopy and Molecular Dynamics Simulations

HIV-1 entry into cells is mediated by the fusion protein gp41. Cholesterol plays an important role in this virus-cell fusion, but molecular structural information about cholesterol-gp41 interaction is so far absent. Here, we present experimental and computational data about cholesterol complexation...

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Detaylı Bibliyografya
Yayımlandı:J Mol Biol
Asıl Yazarlar: Kwon, Byungsu, Mandal, Taraknath, Elkins, Matthew R., Oh, Younghoon, Cui, Qiang, Hong, Mei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7781112/
https://ncbi.nlm.nih.gov/pubmed/32592698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.06.017
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