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Solid-state NMR spectroscopy of the HIV gp41 membrane fusion protein supports intermolecular antiparallel β sheet fusion peptide structure in the final six-helix bundle state

The HIV gp41 protein catalyzes fusion between viral and target cell membranes. Although the ~20-residue N-terminal fusion peptide (FP) region is critical for fusion, the structure of this region is not well-characterized in large gp41 constructs that model the gp41 state at different times during fu...

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Hlavní autoři: Sackett, Kelly, Nethercott, Matthew J., Zheng, Zhaoxiong, Weliky, David P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944376/
https://ncbi.nlm.nih.gov/pubmed/24246500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.11.010
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