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Comparative analysis of membrane-associated fusion peptide secondary structure and lipid mixing function of HIV gp41 constructs which model the early pre-Hairpin intermediate and final Hairpin conformations
Fusion between viral and host cell membranes is the initial step of HIV infection and is mediated by the gp41 protein which is embedded in the viral membrane. The ~20-residue N-terminal fusion peptide (FP) region of gp41 binds to the host cell membrane and plays a critical role in fusion catalysis....
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2830311/ https://ncbi.nlm.nih.gov/pubmed/20080102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.01.018 |
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