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Folded Monomers and Hexamers of the Ectodomain of the HIV gp41 Membrane Fusion Protein: Potential Roles in Fusion and Synergy Between the Fusion Peptide, Hairpin, and Membrane-Proximal External Region

[Image: see text] HIV is an enveloped virus and fusion between the HIV and host cell membranes is catalyzed by the ectodomain of the HIV gp41 membrane protein. Both the N-terminal fusion peptide (FP) and C-terminal membrane-proximal external region (MPER) are critical for fusion and are postulated t...

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Veröffentlicht in:Biochemistry
Hauptverfasser: Banerjee, Koyeli, Weliky, David P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245979/
https://ncbi.nlm.nih.gov/pubmed/25372604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501159w
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