Constitutive role of the Fanconi anemia D2 gene in the replication stress response

In response to DNA cross-linking damage, the Fanconi anemia (FA) core complex activates the FA pathway by monoubiquitinating Fanconi anemia complementation group D2 (FANCD2) for the initiation of the nucleolytic processing of the DNA cross-links and stabilization of stalled replication forks. Given...

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Udgivet i:J Biol Chem
Main Authors: Tian, Yanyan, Shen, Xi, Wang, Rui, Klages-Mundt, Naeh L., Lynn, Erica J., Martin, Sara K., Ye, Yin, Gao, Min, Chen, Junjie, Schlacher, Katharina, Li, Lei
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2017
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5724005/
https://ncbi.nlm.nih.gov/pubmed/29021208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.814780
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