The ARK Assay Is a Sensitive and Versatile Method for the Global Detection of DNA-Protein Crosslinks

DNA-protein crosslinks (DPCs) are a frequent form of DNA lesion and are strongly inhibitive in diverse DNA transactions. Despite recent developments, the biochemical detection of DPCs remains a limiting factor for the in-depth mechanistic understanding of DPC repair. Here, we develop a sensitive and...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Hu, Qianghua, Klages-Mundt, Naeh, Wang, Rui, Lynn, Erica, Saha, Liton Kuma, Zhang, Huimin, Srivastava, Mrinal, Shen, Xi, Tian, Yanyan, Kim, Hyeung, Ye, Yin, Paull, Tanya, Takeda, Shunichi, Chen, Junjie, Li, Lei
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069250/
https://ncbi.nlm.nih.gov/pubmed/31995761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.12.067
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