A systematic review of test accuracy studies evaluating molecular micro-satellite instability testing for the detection of individuals with lynch syndrome

BACKGROUND: A systematic review was conducted to assess the diagnostic test accuracy of polymerase chain reaction (PCR)-based microsatellite instability (MSI) testing for identifying Lynch syndrome in patients with colorectal cancer (CRC). Unlike previous reviews, this was based on assessing MSI tes...

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Vydáno v:BMC Cancer
Hlavní autoři: Coelho, Helen, Jones-Hughes, Tracey, Snowsill, Tristan, Briscoe, Simon, Huxley, Nicola, Frayling, Ian M., Hyde, Chris
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5723028/
https://ncbi.nlm.nih.gov/pubmed/29221446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3820-5
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