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BRCA mutations in the manifestation and treatment of ovarian cancer
BRCA genes are important for the integrity and stability of genetic material and play key roles in repairing DNA breaks via high fidelity homologous recombination. BRCA mutations are known to predispose carriers to gynecological malignancies, accounting for a majority of hereditary OC cases. Known t...
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| Publicat a: | Oncotarget |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5722593/ https://ncbi.nlm.nih.gov/pubmed/29228641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18280 |
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