BRCA Mutation Frequency and Patterns of Treatment Response in BRCA Mutation–Positive Women With Ovarian Cancer: A Report From the Australian Ovarian Cancer Study Group

PURPOSE: The frequency of BRCA1 and BRCA2 germ-line mutations in women with ovarian cancer is unclear; reports vary from 3% to 27%. The impact of germ-line mutation on response requires further investigation to understand its impact on treatment planning and clinical trial design. PATIENTS AND METHO...

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Detalhes bibliográficos
Main Authors: Alsop, Kathryn, Fereday, Sian, Meldrum, Cliff, deFazio, Anna, Emmanuel, Catherine, George, Joshy, Dobrovic, Alexander, Birrer, Michael J., Webb, Penelope M., Stewart, Colin, Friedlander, Michael, Fox, Stephen, Bowtell, David, Mitchell, Gillian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2012
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413277/
https://ncbi.nlm.nih.gov/pubmed/22711857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2011.39.8545
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