Germline mutation in BRCA1 or BRCA2 and ten-year survival for women diagnosed with epithelial ovarian cancer

PURPOSE: To analyse the effect of germline mutations in BRCA1 and BRCA2 on mortality in ovarian cancer patients up to ten years after diagnosis. EXPERIMENTAL DESIGN: We used unpublished survival time data for 2,242 patients from two case-control studies and extended survival-time data for 4,314 pati...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Candido-dos-Reis, Francisco J., Song, Honglin, Goode, Ellen L., Cunningham, Julie M., Fridley, Brooke L., Larson, Melissa C., Alsop, Kathryn, Dicks, Ed, Harrington, Patricia, Ramus, Susan J., de Fazio, Anna, Mitchell, Gillian, Fereday, Sian, Bolton, Kelly L., Gourley, Charlie, Michie, Caroline, Karlan, Beth, Lester, Jenny, Walsh, Christine, Cass, Ilana, Olsson, Håkan, Gore, Martin, Benitez, Javier J., Garcia, Maria J., Andrulis, Irene, Mulligan, Anna Marie, Glendon, Gord, Blanco, Ignacio, Lazaro, Conxi, Whittemore, Alice S., McGuire, Valerie, Sieh, Weiva, Montagna, Marco, Alducci, Elisa, Sadetzki, Siegal, Chetrit, Angela, Kwong, Ava, Kjaer, Susanne K., Jensen, Allan, Høgdall, Estrid, Neuhausen, Susan, Nussbaum, Robert, Daly, Mary, Greene, Mark H., Mai, Phuong L., Loud, Jennifer T., Moysich, Kirsten, Toland, Amanda E., Lambrechts, Diether, Ellis, Steve, Frost, Debra, Brenton, James D., Tischkowitz, Marc, Easton, Douglas F., Antoniou, Antonis, Chenevix-Trench, Georgia, Gayther, Simon A., Bowtell, David, Pharoah, Paul D. P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338615/
https://ncbi.nlm.nih.gov/pubmed/25398451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2497
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