Mutation of ERBB2 Provides a Novel Alternative Mechanism for the Ubiquitous Activation of RAS-MAPK in Ovarian Serous Low Malignant Potential Tumors

Approximately, 10% to 15% of serous ovarian tumors fall into the category designated as tumors of low malignant potential (LMP). Like their invasive counterparts, LMP tumors may be associated with extraovarian disease, for example, in the peritoneal cavity and regional lymph nodes. However, unlike t...

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Pubblicato in:Mol Cancer Res
Autori principali: Anglesio, Michael S., Arnold, Jeremy M., George, Joshy, Tinker, Anna V., Tothill, Richard, Waddell, Nic, Simms, Lisa, Locandro, Bianca, Fereday, Sian, Traficante, Nadia, Russell, Peter, Sharma, Raghwa, Birrer, Michael J., deFazio, Anna, Chenevix-Trench, Georgia, Bowtell, David D.L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6953412/
https://ncbi.nlm.nih.gov/pubmed/19010816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-08-0193
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