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Spotlight on olaparib in the treatment of BRCA-mutated ovarian cancer: design, development and place in therapy

Epithelial ovarian cancer is the sixth most common cancer among women worldwide and the first cause of death among gynecological malignancies. Most of the patients present recurrent disease and unfortunately cannot be cured. The unsatisfactory results obtained with salvage chemotherapy have elicited...

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Enregistré dans:
Détails bibliographiques
Publié dans:Drug Des Devel Ther
Auteurs principaux: Lorusso, Domenica, Tripodi, Elisa, Maltese, Giuseppa, Lepori, Stefano, Sabatucci, Ilaria, Bogani, Giorgio, Raspagliesi, Francesco
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983012/
https://ncbi.nlm.nih.gov/pubmed/29881257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S124447
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