iRhom2 is essential for innate immunity to RNA virus by antagonizing ER- and mitochondria-associated degradation of VISA

VISA (also known as MAVS, IPS-1 and Cardif) is an essential adaptor protein in innate immune response to RNA virus. The protein level of VISA is delicately regulated before and after viral infection to ensure the optimal activation and timely termination of innate antiviral response. It has been rep...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Luo, Wei-Wei, Li, Shu, Li, Chen, Zheng, Zhou-Qin, Cao, Pan, Tong, Zhen, Lian, Huan, Wang, Su-Yun, Shu, Hong-Bing, Wang, Yan-Yi
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722342/
https://ncbi.nlm.nih.gov/pubmed/29155878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006693
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