Restoration of replication fork stability in BRCA1- and BRCA2-deficient cells by inactivation of SNF2-family fork remodelers

To ensure the completion of DNA replication and maintenance of genome integrity, DNA repair factors protect stalled replication forks upon replication stress. Previous studies have identified a critical role for the tumor suppressors BRCA1 and BRCA2 in preventing the degradation of nascent DNA by th...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Taglialatela, Angelo, Alvarez, Silvia, Leuzzi, Giuseppe, Sannino, Vincenzo, Ranjha, Lepakshi, Huang, Jen-Wei, Madubata, Chioma, Anand, Roopesh, Levy, Brynn, Rabadan, Raul, Cejka, Petr, Costanzo, Vincenzo, Ciccia, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5720682/
https://ncbi.nlm.nih.gov/pubmed/29053959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.09.036
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