Restoration of replication fork stability in BRCA1- and BRCA2-deficient cells by inactivation of SNF2-family fork remodelers

To ensure the completion of DNA replication and maintenance of genome integrity, DNA repair factors protect stalled replication forks upon replication stress. Previous studies have identified a critical role for the tumor suppressors BRCA1 and BRCA2 in preventing the degradation of nascent DNA by th...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Cell
Autori principali: Taglialatela, Angelo, Alvarez, Silvia, Leuzzi, Giuseppe, Sannino, Vincenzo, Ranjha, Lepakshi, Huang, Jen-Wei, Madubata, Chioma, Anand, Roopesh, Levy, Brynn, Rabadan, Raul, Cejka, Petr, Costanzo, Vincenzo, Ciccia, Alberto
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5720682/
https://ncbi.nlm.nih.gov/pubmed/29053959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.09.036
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi