Myc Cooperates with Ras by Programming Inflammation and Immune Suppression

The two oncogenes KRas and Myc cooperate to drive tumorigenesis, but the mechanism underlying this remains unclear. In a mouse lung model of KRas(G12D)-driven adenomas, we find that co-activation of Myc drives the immediate transition to highly proliferative and invasive adenocarcinomas marked by hi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell
Main Authors: Kortlever, Roderik M., Sodir, Nicole M., Wilson, Catherine H., Burkhart, Deborah L., Pellegrinet, Luca, Brown Swigart, Lamorna, Littlewood, Trevor D., Evan, Gerard I.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5720393/
https://ncbi.nlm.nih.gov/pubmed/29195074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.11.013
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados