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ROLES OF TRINUCLEOTIDE REPEAT RNA IN NEUROLOGICAL DISEASE AND DEGENERATION

A large number of human diseases are caused by expansion of repeat sequences—typically trinucleotide repeats—within the respective disease genes. The abnormally expanded sequence can lead to a variety of effects on the consequent gene: sometimes the gene is silenced, but in many cases the expanded r...

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Detalhes bibliográficos
Publicado no:Trends Neurosci
Main Authors: Li, Ling-Bo, Bonini, Nancy M
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5720136/
https://ncbi.nlm.nih.gov/pubmed/20398949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2010.03.004
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