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New roles for canonical transcription factors in repeat expansion diseases
The presence of microsatellite repeat expansions within genes is associated with >30 neurological diseases. Of interest, (GGGGCC)(>30)-repeats within C9orf72 are associated with amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD). These expansions can be 100’s to 1000’s of unit...
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| 出版年: | Trends Genet |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6980727/ https://ncbi.nlm.nih.gov/pubmed/31837826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2019.11.003 |
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