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RNA toxicity is a component of ataxin-3 degeneration in Drosophila

Polyglutamine (polyQ) diseases are a class of dominantly-inherited neurodegenerative disorders caused by the expansion of a CAG repeat encoding glutamine within the coding region of the respective genes 1. The molecular and cellular pathways underlying polyQ-induced neurodegeneration are the focus o...

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Bibliografske podrobnosti
Main Authors: Li, Ling-Bo, Yu, Zhenming, Teng, Xiuyin, Bonini, Nancy M.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574630/
https://ncbi.nlm.nih.gov/pubmed/18449188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06909
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