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Triplet Repeat–Derived siRNAs Enhance RNA–Mediated Toxicity in a Drosophila Model for Myotonic Dystrophy
More than 20 human neurological and neurodegenerative diseases are caused by simple DNA repeat expansions; among these, non-coding CTG repeat expansions are the basis of myotonic dystrophy (DM1). Recent work, however, has also revealed that many human genes have anti-sense transcripts, raising the p...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060073/ https://ncbi.nlm.nih.gov/pubmed/21437269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001340 |
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