HIV Env conserved element DNA vaccine alters immunodominance in macaques

Sequence diversity and immunodominance are major obstacles in the design of an effective vaccine against HIV. HIV Env is a highly-glycosylated protein composed of ‘conserved’ and ‘variable’ regions. The latter contains immunodominant epitopes that are frequently targeted by the immune system resulti...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Hu, Xintao, Valentin, Antonio, Rosati, Margherita, Manocheewa, Siriphan, Alicea, Candido, Chowdhury, Bhabadeb, Bear, Jenifer, Broderick, Kate E., Sardesai, Niranjan Y., Gall, Sylvie Le, Mullins, James I., Pavlakis, George N., Felber, Barbara K.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718827/
https://ncbi.nlm.nih.gov/pubmed/28678607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2017.1339852
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