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Comparison of immune responses generated by optimized DNA vaccination against SIV antigens in mice and macaques

Optimized DNA vectors were constructed comprising the proteome of SIV including the structural, enzymatic, regulatory, and accessory proteins. In addition to native antigens as produced by the virus, fusion proteins and modified antigens with altered secretion, cellular localization and stability ch...

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Detalhes bibliográficos
Main Authors: Kulkarni, Viraj, Jalah, Rashmi, Ganneru, Brunda, Bergamaschi, Cristina, Alicea, Candido, von Gegerfelt, Agneta, Patel, Vainav, Zhang, Gen-Mu, Chowdhury, Bhabadeb, Broderick, Kate E., Sardesai, Niranjan Y., Valentin, Antonio, Rosati, Margherita, Felber, Barbara K., Pavlakis, George N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115438/
https://ncbi.nlm.nih.gov/pubmed/21195080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.12.056
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