Comparison of immune responses generated by optimized DNA vaccination against SIV antigens in mice and macaques

Optimized DNA vectors were constructed comprising the proteome of SIV including the structural, enzymatic, regulatory, and accessory proteins. In addition to native antigens as produced by the virus, fusion proteins and modified antigens with altered secretion, cellular localization and stability ch...

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Main Authors: Kulkarni, Viraj, Jalah, Rashmi, Ganneru, Brunda, Bergamaschi, Cristina, Alicea, Candido, von Gegerfelt, Agneta, Patel, Vainav, Zhang, Gen-Mu, Chowdhury, Bhabadeb, Broderick, Kate E., Sardesai, Niranjan Y., Valentin, Antonio, Rosati, Margherita, Felber, Barbara K., Pavlakis, George N.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115438/
https://ncbi.nlm.nih.gov/pubmed/21195080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.12.056
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