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Pharmacological Rac1 inhibitors with selective apoptotic activity in human acute leukemic cell lines
Rac1 GTPase has long been recognized as a critical regulatory protein in different cellular and molecular processes involved in cancer progression, including acute myeloid leukemia. Here we show the antitumoral activity of ZINC69391 and 1A-116, two chemically-related Rac1 pharmacological inhibitors,...
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| Publicat a: | Oncotarget |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5716746/ https://ncbi.nlm.nih.gov/pubmed/29228706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21533 |
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