G2/M Cell Cycle Arrest and Tumor Selective Apoptosis of Acute Leukemia Cells by a Promising Benzophenone Thiosemicarbazone Compound

Anti-mitotic therapies have been considered a hallmark in strategies against abnormally proliferating cells. Focusing on the extensively studied family of thiosemicarbazone (TSC) compounds, we have previously identified 4,4’-dimethoxybenzophenone thiosemicarbazone (T44Bf) as a promising pharmacologi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cabrera, Maia, Gomez, Natalia, Remes Lenicov, Federico, Echeverría, Emiliana, Shayo, Carina, Moglioni, Albertina, Fernández, Natalia, Davio, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567328/
https://ncbi.nlm.nih.gov/pubmed/26360247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136878
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