G2/M Cell Cycle Arrest and Tumor Selective Apoptosis of Acute Leukemia Cells by a Promising Benzophenone Thiosemicarbazone Compound

Anti-mitotic therapies have been considered a hallmark in strategies against abnormally proliferating cells. Focusing on the extensively studied family of thiosemicarbazone (TSC) compounds, we have previously identified 4,4’-dimethoxybenzophenone thiosemicarbazone (T44Bf) as a promising pharmacologi...

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Vydáno v:PLoS One
Hlavní autoři: Cabrera, Maia, Gomez, Natalia, Remes Lenicov, Federico, Echeverría, Emiliana, Shayo, Carina, Moglioni, Albertina, Fernández, Natalia, Davio, Carlos
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567328/
https://ncbi.nlm.nih.gov/pubmed/26360247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136878
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