The Regulator of G Protein Signaling Homologous Domain of G Protein-Coupled Receptor Kinase 2 Mediates Short-Term Desensitization of β3-Adrenergic Receptor

G protein coupled receptor (GPCR) kinases (GRKs) are key regulators of GPCR signaling. Canonical mechanism of GPCR desensitization involves receptor phosphorylation by GRKs followed by arrestin recruitment and uncoupling from heterotrimeric G protein. Although β3-adrenergic receptor (β3AR) lacks pho...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Echeverría, Emiliana, Cabrera, Maia, Burghi, Valeria, Sosa, Máximo, Ripoll, Sonia, Yaneff, Agustín, Monczor, Federico, Davio, Carlos, Shayo, Carina, Fernández, Natalia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7047201/
https://ncbi.nlm.nih.gov/pubmed/32153413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00113
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados