Iron depletion is a novel therapeutic strategy to target cancer stem cells

Adequate iron levels are essential for human health. However, iron overload can act as catalyst for the formation of free radicals, which may cause cancer. Cancer stem cells (CSCs), which maintain the hallmark stem cell characteristics of self-renewal and differentiation capacity, have been proposed...

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Udgivet i:Oncotarget
Main Authors: Ninomiya, Takayuki, Ohara, Toshiaki, Noma, Kazuhiro, Katsura, Yuki, Katsube, Ryoichi, Kashima, Hajime, Kato, Takuya, Tomono, Yasuko, Tazawa, Hiroshi, Kagawa, Shunsuke, Shirakawa, Yasuhiro, Kimura, Fumiaki, Chen, Ling, Kasai, Tomonari, Seno, Masaharu, Matsukawa, Akihiro, Fujiwara, Toshiyoshi
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716739/
https://ncbi.nlm.nih.gov/pubmed/29228699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21846
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