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Iron depletion is a novel therapeutic strategy to target cancer stem cells

Adequate iron levels are essential for human health. However, iron overload can act as catalyst for the formation of free radicals, which may cause cancer. Cancer stem cells (CSCs), which maintain the hallmark stem cell characteristics of self-renewal and differentiation capacity, have been proposed...

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發表在:Oncotarget
Main Authors: Ninomiya, Takayuki, Ohara, Toshiaki, Noma, Kazuhiro, Katsura, Yuki, Katsube, Ryoichi, Kashima, Hajime, Kato, Takuya, Tomono, Yasuko, Tazawa, Hiroshi, Kagawa, Shunsuke, Shirakawa, Yasuhiro, Kimura, Fumiaki, Chen, Ling, Kasai, Tomonari, Seno, Masaharu, Matsukawa, Akihiro, Fujiwara, Toshiyoshi
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716739/
https://ncbi.nlm.nih.gov/pubmed/29228699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21846
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