A Novel Combination Cancer Therapy with Iron Chelator Targeting Cancer Stem Cells via Suppressing Stemness

Excess iron causes cancer and is thought to be related to carcinogenesis and cancer progression including stemness, but the details remain unclear. Here, we hypothesized that stemness in cancer is related to iron metabolism and that regulating iron metabolism in cancer stem cells (CSCs) may be a nov...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Katsura, Yuki, Ohara, Toshiaki, Noma, Kazuhiro, Ninomiya, Takayuki, Kashima, Hajime, Kato, Takuya, Sato, Hiroaki, Komoto, Satoshi, Narusaka, Toru, Tomono, Yasuko, Xing, Boyi, Chen, Yuehua, Tazawa, Hiroshi, Kagawa, Shunsuke, Shirakawa, Yasuhiro, Kasai, Tomonari, Seno, Masaharu, Matsukawa, Akihiro, Fujiwara, Toshiyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6406536/
https://ncbi.nlm.nih.gov/pubmed/30717462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11020177
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