A Novel Combination Cancer Therapy with Iron Chelator Targeting Cancer Stem Cells via Suppressing Stemness

Excess iron causes cancer and is thought to be related to carcinogenesis and cancer progression including stemness, but the details remain unclear. Here, we hypothesized that stemness in cancer is related to iron metabolism and that regulating iron metabolism in cancer stem cells (CSCs) may be a nov...

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Publicat a:Cancers (Basel)
Autors principals: Katsura, Yuki, Ohara, Toshiaki, Noma, Kazuhiro, Ninomiya, Takayuki, Kashima, Hajime, Kato, Takuya, Sato, Hiroaki, Komoto, Satoshi, Narusaka, Toru, Tomono, Yasuko, Xing, Boyi, Chen, Yuehua, Tazawa, Hiroshi, Kagawa, Shunsuke, Shirakawa, Yasuhiro, Kasai, Tomonari, Seno, Masaharu, Matsukawa, Akihiro, Fujiwara, Toshiyoshi
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6406536/
https://ncbi.nlm.nih.gov/pubmed/30717462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11020177
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