Iron depletion enhances the effect of sorafenib in hepatocarcinoma

Human hepatocellular carcinoma (HCC) is known to have a poor prognosis. Sorafenib, a molecular targeted drug, is most commonly used for HCC treatment. However, its effect on HCC is limited in clinical use and therefore new strategies regarding sorafenib treatment are required. Iron overload is known...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Urano, Shinichi, Ohara, Toshiaki, Noma, Kazuhiro, Katsube, Ryoichi, Ninomiya, Takayuki, Tomono, Yasuko, Tazawa, Hiroshi, Kagawa, Shunsuke, Shirakawa, Yasuhiro, Kimura, Fumiaki, Nouso, Kazuhiro, Matsukawa, Akihiro, Yamamoto, Kazuhide, Fujiwara, Toshiyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990399/
https://ncbi.nlm.nih.gov/pubmed/27089255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1177677
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