The regulatory role of aberrant Phosphatase and Tensin Homologue and Liver Kinase B1 on AKT/mTOR/c-Myc axis in pancreatic neuroendocrine tumors

Pancreatic neuroendocrine tumor (pNET) is an uncommon type of pancreatic neoplasm. Low Phosphatase and Tensin Homologue (PTEN) expression and activation of the mechanistic target of rapamycin (mTOR) pathway have been noted in pNETs, and the former is associated with poor survival in pNET patients. B...

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Pubblicato in:Oncotarget
Autori principali: Chang, Tsung-Ming, Shan, Yan-Shen, Chu, Pei-Yi, Jiang, Shih Sheng, Hung, Wen-Chun, Chen, Yu-Lin, Tu, Hsiu-Chi, Lin, Hui-You, Tsai, Hui-Jen, Chen, Li-Tzong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716714/
https://ncbi.nlm.nih.gov/pubmed/29228674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20956
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