The regulatory role of aberrant Phosphatase and Tensin Homologue and Liver Kinase B1 on AKT/mTOR/c-Myc axis in pancreatic neuroendocrine tumors

Pancreatic neuroendocrine tumor (pNET) is an uncommon type of pancreatic neoplasm. Low Phosphatase and Tensin Homologue (PTEN) expression and activation of the mechanistic target of rapamycin (mTOR) pathway have been noted in pNETs, and the former is associated with poor survival in pNET patients. B...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chang, Tsung-Ming, Shan, Yan-Shen, Chu, Pei-Yi, Jiang, Shih Sheng, Hung, Wen-Chun, Chen, Yu-Lin, Tu, Hsiu-Chi, Lin, Hui-You, Tsai, Hui-Jen, Chen, Li-Tzong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716714/
https://ncbi.nlm.nih.gov/pubmed/29228674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20956
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