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Phosphatase and tensin homologue: a therapeutic target for SMA

Spinal muscular atrophy (SMA) is one of the most common juvenile neurodegenerative diseases, which can be associated with child mortality. SMA is caused by a mutation of ubiquitously expressed gene, Survival Motor Neuron1 (SMN1), leading to reduced SMN protein and the motor neuron death. The disease...

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Pubblicato in:Signal Transduct Target Ther
Autori principali: Godena, Vinay K, Ning, Ke
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661640/
https://ncbi.nlm.nih.gov/pubmed/29263925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sigtrans.2017.38
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