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Phosphatase and Tensin Homologue: Novel Regulation by Developmental Signaling

Phosphatase and tensin homologue (PTEN) is a critical cell endogenous inhibitor of phosphoinositide signaling in mammalian cells. PTEN dephosphorylates phosphoinositide trisphosphate (PIP(3)), and by so doing PTEN has the function of negative regulation of Akt, thereby inhibiting this key intracellu...

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Bibliografiska uppgifter
I publikationen:J Signal Transduct
Huvudupphovsman: Jerde, Travis J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi Publishing Corporation 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539077/
https://ncbi.nlm.nih.gov/pubmed/26339505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/282567
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