PTEN regulates spindle assembly checkpoint timing through MAD1 in interphase

The spindle assembly checkpoint (SAC) restrains anaphase progression to ensure all chromosomes attach properly to the spindle. Although SAC timing has been extensively investigated in mitosis, its mechanism of regulation in interphase is unclear. We report that PTEN functions as a crucial activator...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Liu, Yu, Du, Xiao, Zhang, Shuting, Liu, Yang, Zhang, Qiaoling, Yin, Qi, McNutt, Michael A., Yin, Yuxin
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716712/
https://ncbi.nlm.nih.gov/pubmed/29228672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20532
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