PTEN regulates spindle assembly checkpoint timing through MAD1 in interphase

The spindle assembly checkpoint (SAC) restrains anaphase progression to ensure all chromosomes attach properly to the spindle. Although SAC timing has been extensively investigated in mitosis, its mechanism of regulation in interphase is unclear. We report that PTEN functions as a crucial activator...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Yu, Du, Xiao, Zhang, Shuting, Liu, Yang, Zhang, Qiaoling, Yin, Qi, McNutt, Michael A., Yin, Yuxin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716712/
https://ncbi.nlm.nih.gov/pubmed/29228672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20532
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