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Asymmetric Petasis Borono-Mannich Allylation Reactions Catalyzed by Chiral Biphenols

Chiral biphenols catalyze the asymmetric Petasis borono–Mannich allylation of aldehydes and amines through the use of a bench-stable allyldioxaborolane. The reaction proceeds via a two-step, one-pot process and requires 2 – 8 mol% of 3,3’-Ph(2)-BINOL as the optimal catalyst. Under microwave heating...

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Publicat a:Angew Chem Int Ed Engl
Autors principals: Jiang, Yao, Schaus, Scott E.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716625/
https://ncbi.nlm.nih.gov/pubmed/28052567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201611332
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