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CD1b-mycolic acid tetramers demonstrate T cell fine specificity for mycobacterial lipid tails

Mycobacterium tuberculosis synthesizes a thick cell wall comprised of mycolic acids (MA), which are foreign antigens for human T cells. T cell clones from multiple donors were used to determine the fine-specificity of MA recognition by human αβ T cells. Most CD1-presented lipid antigens contain larg...

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Foilsithe in:Eur J Immunol
Main Authors: Van Rhijn, Ildiko, Iwany, Sarah K., Fodran, Peter, Cheng, Tan-Yun, Gapin, Laurent, Minnaard, Adriaan J., Moody, D. Branch
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716475/
https://ncbi.nlm.nih.gov/pubmed/28665555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201747062
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