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CD1b-mycolic acid tetramers demonstrate T cell fine specificity for mycobacterial lipid tails
Mycobacterium tuberculosis synthesizes a thick cell wall comprised of mycolic acids (MA), which are foreign antigens for human T cells. T cell clones from multiple donors were used to determine the fine-specificity of MA recognition by human αβ T cells. Most CD1-presented lipid antigens contain larg...
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| Publicado en: | Eur J Immunol |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5716475/ https://ncbi.nlm.nih.gov/pubmed/28665555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201747062 |
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