Total Synthesis of a Mycolic Acid from Mycobacterium tuberculosis

In Mycobacterium tuberculosis, mycolic acids and their glycerol, glucose, and trehalose esters (“cord factor”) form the main part of the mycomembrane. Despite their first isolation almost a century ago, full stereochemical evaluation is lacking, as is a scalable synthesis required for accurate immun...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Tahiri, Nabil, Fodran, Peter, Jayaraman, Dhineshkumar, Buter, Jeffrey, Witte, Martin D., Ocampo, Tonatiuh A., Moody, D. Branch, Van Rhijn, Ildiko, Minnaard, Adriaan J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7216993/
https://ncbi.nlm.nih.gov/pubmed/32067294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202000523
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