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An apicosome initiates self-organizing morphogenesis of human pluripotent stem cells
Human pluripotent stem cells (hPSCs) self-organize into apicobasally polarized cysts, reminiscent of the lumenal epiblast stage, providing a model to explore key morphogenic processes in early human embryos. Here, we show that apical polarization begins on the interior of single hPSCs through the dy...
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| Udgivet i: | J Cell Biol |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5716285/ https://ncbi.nlm.nih.gov/pubmed/29021220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201704085 |
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