An apicosome initiates self-organizing morphogenesis of human pluripotent stem cells

Human pluripotent stem cells (hPSCs) self-organize into apicobasally polarized cysts, reminiscent of the lumenal epiblast stage, providing a model to explore key morphogenic processes in early human embryos. Here, we show that apical polarization begins on the interior of single hPSCs through the dy...

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Dades bibliogràfiques
Publicat a:J Cell Biol
Autors principals: Taniguchi, Kenichiro, Shao, Yue, Townshend, Ryan F., Cortez, Chari L., Harris, Clair E., Meshinchi, Sasha, Kalantry, Sundeep, Fu, Jianping, O’Shea, K. Sue, Gumucio, Deborah L.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2017
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716285/
https://ncbi.nlm.nih.gov/pubmed/29021220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201704085
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