Lumen Formation Is an Intrinsic Property of Isolated Human Pluripotent Stem Cells

We demonstrate that dissociated human pluripotent stem cells (PSCs) are intrinsically programmed to form lumens. PSCs form two-cell cysts with a shared apical domain within 20 hr of plating; these cysts collapse to form monolayers after 5 days. Expression of pluripotency markers is maintained throug...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Stem Cell Reports
मुख्य लेखकों: Taniguchi, Kenichiro, Shao, Yue, Townshend, Ryan F., Tsai, Yu-Hwai, DeLong, Cynthia J., Lopez, Shawn A., Gayen, Srimonta, Freddo, Andrew M., Chue, Deming J., Thomas, Dennis J., Spence, Jason R., Margolis, Benjamin, Kalantry, Sundeep, Fu, Jianping, O’Shea, K. Sue, Gumucio, Deborah L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Elsevier 2015
विषय:
Report
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682207/
https://ncbi.nlm.nih.gov/pubmed/26626176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.10.015
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