Lumen Formation Is an Intrinsic Property of Isolated Human Pluripotent Stem Cells
We demonstrate that dissociated human pluripotent stem cells (PSCs) are intrinsically programmed to form lumens. PSCs form two-cell cysts with a shared apical domain within 20 hr of plating; these cysts collapse to form monolayers after 5 days. Expression of pluripotency markers is maintained throug...
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| Hlavní autoři: | , , , , , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Elsevier
2015-12-01
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| Edice: | Stem Cell Reports |
| On-line přístup: | http://www.sciencedirect.com/science/article/pii/S2213671115003124 |
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