Lumen Formation Is an Intrinsic Property of Isolated Human Pluripotent Stem Cells

We demonstrate that dissociated human pluripotent stem cells (PSCs) are intrinsically programmed to form lumens. PSCs form two-cell cysts with a shared apical domain within 20 hr of plating; these cysts collapse to form monolayers after 5 days. Expression of pluripotency markers is maintained throug...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Taniguchi, Kenichiro, Shao, Yue, Townshend, Ryan F., Tsai, Yu-Hwai, DeLong, Cynthia J., Lopez, Shawn A., Gayen, Srimonta, Freddo, Andrew M., Chue, Deming J., Thomas, Dennis J., Spence, Jason R., Margolis, Benjamin, Kalantry, Sundeep, Fu, Jianping, O’Shea, K. Sue, Gumucio, Deborah L.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682207/
https://ncbi.nlm.nih.gov/pubmed/26626176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.10.015
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