LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning

Signaling from lysosomes controls cellular clearance and energy metabolism. Lysosomal malfunction has been implicated in several pathologies, including neurodegeneration, cancer, infection, immunodeficiency, and obesity. Interestingly, many functions are dependent on the organelle position. Lysosoma...

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Bibliografiska uppgifter
I publikationen:J Cell Biol
Huvudupphovsmän: Filipek, Przemyslaw A., de Araujo, Mariana E.G., Vogel, Georg F., De Smet, Cedric H., Eberharter, Daniela, Rebsamen, Manuele, Rudashevskaya, Elena L., Kremser, Leopold, Yordanov, Teodor, Tschaikner, Philipp, Fürnrohr, Barbara G., Lechner, Stefan, Dunzendorfer-Matt, Theresia, Scheffzek, Klaus, Bennett, Keiryn L., Superti-Furga, Giulio, Lindner, Herbert H., Stasyk, Taras, Huber, Lukas A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2017
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716276/
https://ncbi.nlm.nih.gov/pubmed/28993467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201703061
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