LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning

Signaling from lysosomes controls cellular clearance and energy metabolism. Lysosomal malfunction has been implicated in several pathologies, including neurodegeneration, cancer, infection, immunodeficiency, and obesity. Interestingly, many functions are dependent on the organelle position. Lysosoma...

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發表在:J Cell Biol
Main Authors: Filipek, Przemyslaw A., de Araujo, Mariana E.G., Vogel, Georg F., De Smet, Cedric H., Eberharter, Daniela, Rebsamen, Manuele, Rudashevskaya, Elena L., Kremser, Leopold, Yordanov, Teodor, Tschaikner, Philipp, Fürnrohr, Barbara G., Lechner, Stefan, Dunzendorfer-Matt, Theresia, Scheffzek, Klaus, Bennett, Keiryn L., Superti-Furga, Giulio, Lindner, Herbert H., Stasyk, Taras, Huber, Lukas A.
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2017
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Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716276/
https://ncbi.nlm.nih.gov/pubmed/28993467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201703061
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