LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning

Signaling from lysosomes controls cellular clearance and energy metabolism. Lysosomal malfunction has been implicated in several pathologies, including neurodegeneration, cancer, infection, immunodeficiency, and obesity. Interestingly, many functions are dependent on the organelle position. Lysosoma...

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Bibliografski detalji
Izdano u:J Cell Biol
Glavni autori: Filipek, Przemyslaw A., de Araujo, Mariana E.G., Vogel, Georg F., De Smet, Cedric H., Eberharter, Daniela, Rebsamen, Manuele, Rudashevskaya, Elena L., Kremser, Leopold, Yordanov, Teodor, Tschaikner, Philipp, Fürnrohr, Barbara G., Lechner, Stefan, Dunzendorfer-Matt, Theresia, Scheffzek, Klaus, Bennett, Keiryn L., Superti-Furga, Giulio, Lindner, Herbert H., Stasyk, Taras, Huber, Lukas A.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2017
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716276/
https://ncbi.nlm.nih.gov/pubmed/28993467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201703061
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