LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning

Signaling from lysosomes controls cellular clearance and energy metabolism. Lysosomal malfunction has been implicated in several pathologies, including neurodegeneration, cancer, infection, immunodeficiency, and obesity. Interestingly, many functions are dependent on the organelle position. Lysosoma...

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Pubblicato in:J Cell Biol
Autori principali: Filipek, Przemyslaw A., de Araujo, Mariana E.G., Vogel, Georg F., De Smet, Cedric H., Eberharter, Daniela, Rebsamen, Manuele, Rudashevskaya, Elena L., Kremser, Leopold, Yordanov, Teodor, Tschaikner, Philipp, Fürnrohr, Barbara G., Lechner, Stefan, Dunzendorfer-Matt, Theresia, Scheffzek, Klaus, Bennett, Keiryn L., Superti-Furga, Giulio, Lindner, Herbert H., Stasyk, Taras, Huber, Lukas A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2017
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716276/
https://ncbi.nlm.nih.gov/pubmed/28993467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201703061
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