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LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning
Signaling from lysosomes controls cellular clearance and energy metabolism. Lysosomal malfunction has been implicated in several pathologies, including neurodegeneration, cancer, infection, immunodeficiency, and obesity. Interestingly, many functions are dependent on the organelle position. Lysosoma...
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| 發表在: | J Cell Biol |
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Rockefeller University Press
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5716276/ https://ncbi.nlm.nih.gov/pubmed/28993467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201703061 |
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