Emerging Role of One-Carbon Metabolism and DNA Methylation Enrichment on δ-Containing GABA(A) Receptor Expression in the Cerebellum of Subjects with Alcohol Use Disorders (AUD)

BACKGROUND: Cerebellum is an area of the brain particularly sensitive to the effects of acute and chronic alcohol consumption. Alcohol exposure decreases cerebellar Purkinje cell output by increasing GABA release from Golgi cells onto extrasynaptic α(6)/δ-containing GABA(A) receptors located on glut...

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Veröffentlicht in:Int J Neuropsychopharmacol
Hauptverfasser: Gatta, Eleonora, Auta, James, Gavin, David P, Bhaumik, Dulal K, Grayson, Dennis R, Pandey, Subhash C, Guidotti, Alessandro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
Regular Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716183/
https://ncbi.nlm.nih.gov/pubmed/29020412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyx075
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