Genome-wide methylation in alcohol use disorder subjects: implications for an epigenetic regulation of the cortico-limbic glucocorticoid receptors (NR3C1)

Environmental factors, including substance abuse and stress, cause long-lasting changes in the regulation of gene expression in the brain via epigenetic mechanisms, such as DNA methylation. We examined genome-wide DNA methylation patterns in the prefrontal cortex (PFC, BA10) of 25 pairs of control a...

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Vydáno v:Mol Psychiatry
Hlavní autoři: Gatta, Eleonora, Grayson, Dennis R., Auta, James, Saudagar, Vikram, Dong, Erbo, Chen, Ying, Krishnan, Harish R., Drnevich, Jenny, Pandey, Subhash C., Guidotti, Alessandro
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930366/
https://ncbi.nlm.nih.gov/pubmed/31239533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-019-0449-6
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