Emerging Role of One-Carbon Metabolism and DNA Methylation Enrichment on δ-Containing GABA(A) Receptor Expression in the Cerebellum of Subjects with Alcohol Use Disorders (AUD)

BACKGROUND: Cerebellum is an area of the brain particularly sensitive to the effects of acute and chronic alcohol consumption. Alcohol exposure decreases cerebellar Purkinje cell output by increasing GABA release from Golgi cells onto extrasynaptic α(6)/δ-containing GABA(A) receptors located on glut...

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Détails bibliographiques
Publié dans:Int J Neuropsychopharmacol
Auteurs principaux: Gatta, Eleonora, Auta, James, Gavin, David P, Bhaumik, Dulal K, Grayson, Dennis R, Pandey, Subhash C, Guidotti, Alessandro
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
Sujets:
Regular Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716183/
https://ncbi.nlm.nih.gov/pubmed/29020412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyx075
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