Emerging Role of One-Carbon Metabolism and DNA Methylation Enrichment on δ-Containing GABA(A) Receptor Expression in the Cerebellum of Subjects with Alcohol Use Disorders (AUD)

BACKGROUND: Cerebellum is an area of the brain particularly sensitive to the effects of acute and chronic alcohol consumption. Alcohol exposure decreases cerebellar Purkinje cell output by increasing GABA release from Golgi cells onto extrasynaptic α(6)/δ-containing GABA(A) receptors located on glut...

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Publicado en:Int J Neuropsychopharmacol
Autores principales: Gatta, Eleonora, Auta, James, Gavin, David P, Bhaumik, Dulal K, Grayson, Dennis R, Pandey, Subhash C, Guidotti, Alessandro
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
Materias:
Regular Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716183/
https://ncbi.nlm.nih.gov/pubmed/29020412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyx075
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